Angelman syndrome is a developmental disorder caused by a rare genetic mutation. Symptoms can start in childhood and last for a lifetime It causes developmental delays by affecting the nervous system. Although it shares some clinical characteristics with conditions such as autism and cerebral palsy, the cause is very different. According to the Angelman Syndrome Foundation, more than 500,000 people are suffering from Angelman syndrome worldwide and it occurs in one out of every 15,000 live births. Males and females are both equally prone to develop this disease.
The most common symptoms of Angelman syndrome include speech impairment, movement, and balance problems, a happy, excitable mannerism, and seizures. AS is a genetic disorder caused by a mutation or chromosomal abnormality in the UBE3A gene, which prevents it from functioning properly. The UBE3A gene is passed down from both parents to people without AS. Both the copies corresponding to the gene are seen to be active in certain body parts.
Treating Angelman Syndrome
Angelman syndrome has no known cure as of yet. Symptoms can currently be managed with early treatment. Anti-seizure medications, behavioral therapy and sleep routines to help with sleeping issues, physical therapy, and so on are some of the options. According to some recent studies, the use of CBD oil products could also help in managing the symptoms of this condition.
CBD For Angelman Syndrome
CBD significantly reduced the severity of seizures induced by certain stimuli in a recent mouse study. To refresh your memory, pure CBD is a non-intoxicating cannabinoid that does not cause a high or addiction in those who use it. THC, on the other hand, is a psychoactive compound associated with lung diseases caused by vaping, produces a high, can cause influence, and is associated with the negative effects of marijuana use.
Breastfeeding or pregnant women should not use CBD or THC. The effects of CBD on mice with genetic similarities to humans with Angelman syndrome were investigated in this study. Acute CBD doses of 100 mg were found to reduce seizures in mice caused by loud noises and temperature fluctuations. The researchers also discovered that the acute anticonvulsant CBD had a “mild sedative” effect on the test subjects, but had no impact on balance or motor control.
Final Thoughts
Before you decide to use CBD oil products to manage the symptoms of Angelman syndrome, it is a good idea to consult a doctor because they can help in finding a safe dosage for CBD.